Does the presence of valvular calcification on CCTA predict cardiovascular events independently of coronary artery disease burden in patients with stable chest pain?
While valvular calcification on CCTA is a common finding associated with cardiovascular events, its prognostic value is driven by concomitant coronary artery disease rather than being an independent risk factor.
Aortic and mitral valve calcification occurs in one in six patients with stable chest pain undergoing CCTA and is associated with concomitant coronary atherosclerosis. Whilst valvular calcification is associated with a higher risk of cardiovascular events, this was not independent of the burden of coronary artery disease.
Williams et al. (Mon,) studied this question.
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