P-glycoprotein efflux and the MDR1 C3435T genotype diminish clopidogrel absorption and active metabolite formation.
Clopidogrel absorption and thereby active metabolite formation are diminished by P-gp-mediated efflux and are influenced by the MDR1 C3435T genotype.
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Clinical Pharmacology & Therapeutics
Technical University of Munich
University of Cologne
Deutsches Herzzentrum der Charité
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