Interference with the ISG15 system might be a novel therapeutic approach in viral cardiomyopathy.
The ISG15 conjugation system represents a critical innate response mechanism in cardiomyocytes to fight the battle against invading pathogens, limiting inflammatory cardiomyopathy, heart failure, and death. Interference with the ISG15 system might be a novel therapeutic approach in viral cardiomyopathy.
Rahnefeld et al. (Thu,) studied this question.