Extended Characterisation of the Coding Sequence of the HLA‐C*07:167 Allele by Next and Third‐Generation Sequencing

Key Points

• The aim is to characterize the coding sequence of the HLA-C*07:167 allele and identify its variations.
• Utilized next-generation and third-generation sequencing techniques
• Focused on the coding sequence in exon 4
• Compared HLA-C*07:167 with HLA-C*07:02:01:89
• Identified a single nucleotide substitution in codon 211
• Confirmed structural differences between the two alleles