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April 1, 2026HLA

Extended Characterisation of the Coding Sequence of the HLA‐C*07:167 Allele by Next and Third‐Generation Sequencing

Romain Ferru‐Clément Perrine Augustin Diana Ratiarison Isabelle Jollet

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Key Points

The aim is to characterize the coding sequence of the HLA-C*07:167 allele and identify its variations.
Utilized next-generation and third-generation sequencing techniques
Focused on the coding sequence in exon 4
Compared HLA-C*07:167 with HLA-C*07:02:01:89
Identified a single nucleotide substitution in codon 211
Confirmed structural differences between the two alleles

Implication

Reports the specific nucleotide change in the HLA-C*07:167 allele, indicating genomic variation.

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Cite This Study

Ferru‐Clément et al. (2026) studied this question.

synapsesocial.com/papers/69e07c632f7e8953b7cbdb2c https://doi.org/10.1111/tan.70722

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