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March 25, 2026HLA

Characterisation of the Novel HLA‐C*07:01:124 Allele by Next‐Generation Sequencing

Julien Cliquot Grégory Gatouillat Grégory Salez Marcelle Tonye‐Libyh Delphine Giusti

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Key Points

The aim is to characterise the novel HLA-C*07:01:124 allele and its differences from related alleles.
Conducted genetic analysis using next-generation sequencing.
Focused on nucleotide sequences in exon 1.
Identified differences in codon -13.
HLA-C*07:01:124 differs from HLA-C*07:01:02:01 by a single nucleotide.
This nucleotide change occurs at codon -13.

Implication

This research characterises a new HLA-C allele in a genetic analysis, revealing important nucleotide differences.

Abstract

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Cite This Study

Cliquot et al. (2026) studied this question.

synapsesocial.com/papers/69c771688bbfbc51511e1594 https://doi.org/10.1111/tan.70689

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterization of the Novel <i>HLA‐C*07:01:126</i> Allele by Sequencing‐Based Typing2024 · 2 citations
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4Characterisation of the novel <i>HLA‐C*07:02:151</i> allele by sequencing‐based typing2024 · 3 citations
5Characterisation of the Novel <i>HLA‐C*08:01:37</i> Allele by Next‐Generation Sequencing2025 · 2 citations

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Identification of the Novel HLA‐B*35:670 Allele by Next‐Generation Sequencing in a Bone Marrow DonorHLA · 2026
Description of the Novel HLA‐C*06:414 Allele in a Bone Marrow DonorHLA · 2026

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