Characterization and Clinical Management of Adverse Events Following Treatment with Repotrectinib: A TRIDENT-1 Analysis

Key Points

• This research aims to characterize and manage adverse events following treatment with repotrectinib.
• Analyzed adverse events associated with repotrectinib treatment.
• Evaluated the effectiveness of dose modifications.
• Assessed pharmacologic interventions for managing neurological adverse events.
• Many adverse events were identified following repotrectinib treatment.
• Neurological adverse events were mitigated with appropriate management strategies.
• Dose modifications and pharmacologic interventions proved effective in managing adverse events.