Photo-induced thio/selenocyanation-annulation-rearrangement of indole-tethered 1,6-enynes

Key Points

• This research aims to develop a mild method for constructing diverse indole-based compounds using photo-induced reactions.
• Utilized NH4SCN/KSeCN as reactants in a three-component reaction.
• Employed O2 as both an oxidant and source of dicarbonyl oxygen.
• Designed experiments to facilitate cyclization and rearrangement processes.
• Successful synthesis of thiocyanated/selenocyanated bicarbonyl pyrrolo[1,2-a]indoles.
• Demonstrated the dual role of O2 in the reaction mechanism.
• Achieved diverse product formation through a new mild reaction route.