Photo-induced thio/selenocyanation-annulation-rearrangement of indole-tethered 1,6-enynes

Xueli Wang; Li‐Jun Li; Qinqin Yan; Zhenyi Wang; Zexuan Liu; Jingyi Chen; Zhong-Quan Liu; Zejiang Li

doi:10.1039/d6ob00481d

January 1, 2025Organic & Biomolecular Chemistry

Photo-induced thio/selenocyanation-annulation-rearrangement of indole-tethered 1,6-enynes

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to develop a mild method for constructing diverse indole-based compounds using photo-induced reactions.
Utilized NH4SCN/KSeCN as reactants in a three-component reaction.
Employed O2 as both an oxidant and source of dicarbonyl oxygen.
Designed experiments to facilitate cyclization and rearrangement processes.
Successful synthesis of thiocyanated/selenocyanated bicarbonyl pyrrolo[1,2-a]indoles.
Demonstrated the dual role of O2 in the reaction mechanism.
Achieved diverse product formation through a new mild reaction route.

Abstract

Photo-involved mild three-component thiocyanation/selenocyanation-cyclization-rearrangement of indole-tethered 1,6-enynes, NH4SCN/KSeCN, with O2 was developed to access diverse thiocyanated/selenocyanated bicarbonyl pyrrolo[1,2-a]indoles. O2 acted in dual roles (oxidant and dicarbonyl oxygen source). The rearrangement...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/69e866c96e0dea528ddeb238 https://doi.org/10.1039/d6ob00481d

View Full Paper

Ask AI

Bookmark

Share

Photo-induced thio/selenocyanation-annulation-rearrangement of indole-tethered 1,6-enynes

Key Points

Abstract

Discussion

Cite This Study

Photo-induced thio/selenocyanation-annulation-rearrangement of indole-tethered 1,6-enynes

Key Points

Abstract

Discussion

Cite This Study

Keep reading

More related papers

More from Organic & Biomolecular Chemistry

Keep reading

More related papers

More from Organic & Biomolecular Chemistry