Dual Cross-linked Biodegradable Polyelectrolyte Hydrogel Actuator for Bi-Directional pH-Responsive Drug Release

Key Points

• The aim is to develop a biodegradable hydrogel that releases drugs in response to pH changes.
• Developed a dual cross-linked hydrogel using gelatin and carboxymethyl cellulose (CMC).
• Evaluated pH sensitivity and drug release capabilities of the hydrogel.
• The hydrogel exhibited bi-directional pH-responsiveness.
• Controlled drug release was achieved at different pH levels.