Abstract: This work is Paper 10 of the 9-Keel Unified Theory Series, and serves as the definitive unifying framework for the entire series. All prior inconsistent or deprecated frameworks (including earlier models related to ExO and cancer) are hereby superseded by this single, coherent paradigm: TOFD > C. This paper establishes the fundamental axiom: "Cells have no subjective will, no self-attack behavior, no pathological rebellion." All chronic disease progression is driven by Tissue-Originated Functional Deficiency (TOFD) exceeding homeostatic repair capacity (C, defined as the Ang Constant), rather than autoimmune aggression or cell-intrinsic "misbehavior." This work provides a stable, falsifiable, and publishable theoretical foundation for the interpretation of all chronic diseases, eliminating conceptual inconsistency and strengthening logical closure.
FOO SENG ANG (Tue,) studied this question.
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