Performance of Thromboelastography 6s Difference in Reaction Time Between Heparinase-Free and Heparinase-Containing Channel for Detecting Subtherapeutic Unfractionated Heparin Anticoagulation in a Pediatric Cardiac ICU

Key Points

• This research aims to evaluate the effectiveness of thromboelastography ΔR in detecting subtherapeutic heparin levels in a pediatric cardiac ICU setting.
• Utilized thromboelastography to assess reaction times in heparinase-free and heparinase-containing channels.
• Compared ΔR values with anti-Xa levels to determine correlation and performance.
• ΔR showed a moderate correlation with anti-Xa levels, indicating substantial agreement.
• Demonstrated high discriminative performance in identifying subtherapeutic anticoagulation.