Sodium deprivation in dogs significantly increased renin activity in plasma, urine, and renal cortex (p<0.01), indicating urinary renin excretion correlates with plasma and renal renin activity.
p-value: p=<0.01
SummaryPlasma and urine renin activity were measured in dogs during control diet and sodium deprivation. Renin activity increased in both plasma (p < 0.01) and urine (p < 0.01) in parallel fashion during sodium deprivation and decreased with sodium replacement. In another group of dogs, sodium restriction had the same stimulatory effect on plasma (p < 0.01), urine (p < 0.01), and renal renin activity (p < 0.01). The results indicate that enhanced urinary excretion of renin is directly correlated to the increase in plasma and renal renin activity.
Hayduk et al. (Mon,) conducted a other in Sodium balance. Sodium deprivation vs. Control diet was evaluated on Renin activity in plasma, urine, and renal cortex (p=<0.01). Sodium deprivation in dogs significantly increased renin activity in plasma, urine, and renal cortex (p<0.01), indicating urinary renin excretion correlates with plasma and renal renin activity.