In vivo cardiac dysfunctions observed at low temperatures in rats were attributable to shifts in temperature kinetics of enzyme systems at 20 to 21 C.
Deep hypothermia
Deep hypothermia / temperature changes (5 to 35 C)
Sequential changes in body temperature, heart rate, electrocardiogram, and in vitro myocardial metabolic activity
Deep hypothermia in the rat was studied with respect to the sequential changes in body temperature, heart rate, and electrocardiogram. In vitro assays of myocardial metabolic activity were made at temperatures ranging from 5 to 35 C. These assays strongly suggested that the in vivo cardiac dysfunctions observed at low temperatures were attributable to shifts in temperature kinetics of enzyme systems at 20 to 21 C.
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John P. Hannon (Sat,) conducted a other in Deep hypothermia. Deep hypothermia / temperature changes was evaluated on Sequential changes in body temperature, heart rate, electrocardiogram, and in vitro myocardial metabolic activity. In vivo cardiac dysfunctions observed at low temperatures in rats were attributable to shifts in temperature kinetics of enzyme systems at 20 to 21 C.
synapsesocial.com/papers/6a0cd61efd642a6592d4d85b — DOI: https://doi.org/10.1161/01.res.6.6.771
John P. Hannon
U.S. Army Research Institute of Environmental Medicine
Circulation Research
Orano (United States)
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