What is the clinical evidence from this study?

Study design: Observational. Population: Atrial fibrillation. Intervention: Procainamide vs. Pre-procainamide baseline. Primary outcome: Correlation between the median frequency of the surface and intra-atrial leads (correlation 0.06 to 0.88).

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December 17, 2002

Correspondence between the frequency domain characteristics of simultaneous surface and intra-atrial recordings of atrial fibrillation

Key Result

The correlation between the median frequency of surface ECG leads and intra-atrial recordings during procainamide infusion for atrial fibrillation ranged from 0.06 to 0.88.

Study Design

Type

Observational

Structured PICO

Can changes in the median frequency of atrial fibrillation during procainamide infusion be measured simultaneously and correlate between surface ECG leads and intra-atrial recordings?

Population

Patients with atrial fibrillation

Intervention

Procainamide infusion

Comparator

Pre-procainamide baseline

Outcome

Median frequency of the power spectrum of remainder electrocardiograms (leads II and VI) and intra-atrial leadsurrogate

The correlation between the median frequency of atrial fibrillation measured on surface ECG and intra-atrial recordings varies widely among individual patients.

Main Result

Effect estimate: correlation 0.06 to 0.88

Abstract

Previous studies have shown a decrease in the median frequency of intra-atrial recordings of atrial fibrillation during the infusion of procainamide. This study determines if the changes in median frequency can be measured simultaneously in ECG leads. Remainder electrocardiograms were generated for lead II and VI before and after the administration of procainamide. The median frequency of the power spectrum of the remainder electrocardiograms as well as an intra-atrial lead were calculated. The average median frequency of the pre-procainamide segments ranged from 4.1-6.9 Hz for lead II; 4.1-6.9 Hz for lead VI; and 4.1-7.4 Hz for the intra-atrial lead. The average median frequency of the post-procainamide segments ranged from 4.2-5.8 Hz for lead II; 4.3-5.8 fit for lead VI; and 3.1-6.1 Hz for the intra-atrial lead. Considering each patient individually, correlation between the median frequency of the surface and intra-atrial leads ranged from 0.06 to 0.88.>

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Cite This Study

Slocum et al. (Tue,) conducted a observational in Atrial fibrillation. Procainamide vs. Pre-procainamide baseline was evaluated on Correlation between the median frequency of the surface and intra-atrial leads (correlation 0.06 to 0.88). The correlation between the median frequency of surface ECG leads and intra-atrial recordings during procainamide infusion for atrial fibrillation ranged from 0.06 to 0.88.

synapsesocial.com/papers/6a0ea102b7cc3b883f22924c https://doi.org/https://doi.org/10.1109/cic.1994.470069

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