Key result
The correlation between the median frequency of surface ECG leads and intra-atrial recordings during procainamide infusion for atrial fibrillation ranged from 0.06 to 0.88.
Why the study?
Can changes in the median frequency of atrial fibrillation during procainamide infusion be measured simultaneously and correlate between surface ECG leads and intra-atrial recordings?
Observational
Can changes in the median frequency of atrial fibrillation during procainamide infusion be measured simultaneously and correlate between surface ECG leads and intra-atrial recordings?
Effect estimate: correlation 0.06 to 0.88
The correlation between the median frequency of atrial fibrillation measured on surface ECG and intra-atrial recordings varies widely among individual patients.
Variable surface-to-intra-atrial AF frequency correlation during procainamide leaves open noninvasive monitoring reliability; prospective validation needed.
Previous studies have shown a decrease in the median frequency of intra-atrial recordings of atrial fibrillation during the infusion of procainamide. This study determines if the changes in median frequency can be measured simultaneously in ECG leads. Remainder electrocardiograms were generated for lead II and VI before and after the administration of procainamide. The median frequency of the power spectrum of the remainder electrocardiograms as well as an intra-atrial lead were calculated. The average median frequency of the pre-procainamide segments ranged from 4.1-6.9 Hz for lead II; 4.1-6.9 Hz for lead VI; and 4.1-7.4 Hz for the intra-atrial lead. The average median frequency of the post-procainamide segments ranged from 4.2-5.8 Hz for lead II; 4.3-5.8 fit for lead VI; and 3.1-6.1 Hz for the intra-atrial lead. Considering each patient individually, correlation between the median frequency of the surface and intra-atrial leads ranged from 0.06 to 0.88.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
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Slocum et al. (2002) conducted an observational in Atrial fibrillation. Procainamide vs. Pre-procainamide baseline was evaluated on Correlation between the median frequency of the surface and intra-atrial leads (correlation 0.06 to 0.88). The correlation between the median frequency of surface ECG leads and intra-atrial recordings during procainamide infusion for atrial fibrillation ranged from 0.06 to 0.88.
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