Serum troponin T > 2.8 micrograms/l predicted a left ventricular ejection fraction < 40% after first acute myocardial infarction with 100% sensitivity and 92.9% specificity.
Observational (n=50)
Can serum troponin T concentration measured after a first acute myocardial infarction identify patients with a left ventricular ejection fraction < 40%?
Serum troponin T measurement 12-48 hours after a first myocardial infarction is a highly sensitive and specific non-invasive marker for identifying patients with depressed left ventricular ejection fraction (< 40%).
Effect estimate: AUC 0.9773 (95% CI 0.9409 to 1.0136)
p-value: p=< 0.0001
AIM: To determine whether measurement of serum troponin T concentration after first acute myocardial infarction can be used to identify patients with a left ventricular ejection fraction of 2.8 micrograms/l predicted a left ventricular ejection fraction of < 40% with a sensitivity of 100% (CI 84.6 to 100.0) and specificity of 92.9% (CI 76.5 to 99.1). Exclusion of patients who did not receive thrombolytic treatment did not significantly affect the results. CONCLUSION: Serum troponin T concentration measured 12-48 hours after admission for first myocardial infarction is a reliable, simple, quick, inexpensive, non-invasive method for identifying patients with a left ventricular ejection fraction of < 40% for whom there is a poor prognosis.
Rao et al. (Tue,) conducted a observational in First acute myocardial infarction (n=50). Serum troponin T measurement vs. Angiographic left ventricular ejection fraction was evaluated on Identification of left ventricular ejection fraction < 40% (AUC 0.9773, 95% CI 0.9409 to 1.0136, p=< 0.0001). Serum troponin T > 2.8 micrograms/l predicted a left ventricular ejection fraction < 40% after first acute myocardial infarction with 100% sensitivity and 92.9% specificity.