Key result
Serum troponin T > 2.8 micrograms/l predicted a left ventricular ejection fraction < 40% after first acute myocardial infarction with 100% sensitivity and 92.9% specificity.
Why the study?
Can serum troponin T concentration measured after a first acute myocardial infarction identify patients with a left ventricular ejection fraction < 40%?
Observational (n=50)
Can serum troponin T concentration measured after a first acute myocardial infarction identify patients with a left ventricular ejection fraction < 40%?
Effect estimate: AUC 0.9773 (95% CI 0.9409 to 1.0136)
p-value: p=< 0.0001
Serum troponin T measurement 12-48 hours after a first myocardial infarction is a highly sensitive and specific non-invasive marker for identifying patients with depressed left ventricular ejection fraction (< 40%).
No takes yet. Share an insight, caveat, or question.
May support troponin T as a noninvasive marker for LVEF <40% post-MI; leaves open prospective validation before clinical adoption.
Rao et al. (1998) conducted an observational in First acute myocardial infarction (n=50). Serum troponin T measurement vs. Angiographic left ventricular ejection fraction was evaluated on Identification of left ventricular ejection fraction < 40% (AUC 0.9773, 95% CI 0.9409 to 1.0136, p=< 0.0001). Serum troponin T > 2.8 micrograms/l predicted a left ventricular ejection fraction < 40% after first acute myocardial infarction with 100% sensitivity and 92.9% specificity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: