Does lithium use during pregnancy increase the risk of cardiovascular anomalies and congenital heart disease in exposed infants?
Lithium exposure during pregnancy is associated with a higher than expected risk of cardiovascular anomalies, supporting a conservative prescribing policy for fertile and pregnant women.
The 143 cases of lithium use during pregnancy collected by the Register of Lithium Babies show that infants exposed to lithium appear to have a higher than expected ratio of cardiovascular anomalies to all anomalies and may have an increased risk of congenital heart disease. The authors believe that these findings justify a conservative policy on the use of lithium with fertile and pregnant women.
Weinstein et al. (Thu,) studied this question.
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