Why the study?
Does lithium use during pregnancy increase the risk of cardiovascular anomalies and congenital heart disease in exposed infants?
Does lithium use during pregnancy increase the risk of cardiovascular anomalies and congenital heart disease in exposed infants?
Lithium exposure during pregnancy is associated with a higher than expected risk of cardiovascular anomalies, supporting a conservative prescribing policy for fertile and pregnant women.
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May warrant caution with lithium in pregnancy; leaves open confirmation of congenital heart disease risk in larger studies.
Weinstein et al. (1975) studied this question.
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