Real-time true FISP cine MR imaging evaluated the entire left ventricle in one breath hold, yielding higher myocardium-to-blood CNRs than FLASH and comparable LV function to single-section FISP.
Observational (n=20)
Does real-time true FISP cine MR imaging in a single breath hold provide comparable left ventricular mass and function measurements to single-section true FISP and FLASH MR imaging?
Real-time true FISP cine MR imaging allows for accurate evaluation of left ventricular function in a single breath hold, comparable to standard multi-breath-hold techniques.
In 12 healthy volunteers and eight patients with cardiac disease, cine magnetic resonance (MR) imaging in the heart was performed with real-time true fast imaging with steady-state precession (FISP), which permitted evaluation of the entire left ventricle in one breath hold (91 msec per frame, 13 frames per section position, nine short-axis section positions per breath hold). Contrast-to-noise ratios (CNRs) and left ventricular mass and function measurements with this technique were compared in all subjects with single-section true FISP imaging and, in the volunteers only, with segmented fast low-angle shot (FLASH) MR imaging. Myocardium-to-blood CNR was significantly higher for both true FISP sequences compared with the FLASH sequence. Measurements of resting left ventricular function with real-time true FISP imaging were comparable with those derived from a series of separate breath-hold single-section true FISP acquisitions.
Lee et al. (Fri,) conducted a observational in Healthy volunteers and patients with cardiac disease (n=20). Real-time true FISP cine MR imaging vs. Single-section true FISP imaging and segmented FLASH MR imaging was evaluated on Contrast-to-noise ratios (CNRs) and left ventricular mass and function measurements. Real-time true FISP cine MR imaging evaluated the entire left ventricle in one breath hold, yielding higher myocardium-to-blood CNRs than FLASH and comparable LV function to single-section FISP.