March 1, 2002Radiology
Cardiac Function: MR Evaluation in One Breath Hold with Real-time True Fast Imaging with Steady-State Precession
Key result
Real-time true FISP cine MR imaging evaluated the entire left ventricle in one breath hold, yielding higher myocardium-to-blood CNRs than FLASH and comparable LV function to single-section FISP.
Why the study?
Does real-time true FISP cine MR imaging in a single breath hold provide comparable left ventricular mass and function measurements to single-section true FISP and FLASH MR imaging?
Population
12 healthy volunteers and 8 patients with cardiac disease (n=20)
Comparison
Real-time true fast imaging with steady-state… vs Single-section true FISP imaging and segmented…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support single-breath-hold LV cine MRI clinically; leaves open routine adoption pending prospective validation.
Study Design
Type
Observational (n=20)
Structured PICO
Does real-time true FISP cine MR imaging in a single breath hold provide comparable left ventricular mass and function measurements to single-section true FISP and FLASH MR imaging?
P
Population
12 healthy volunteers and 8 patients with cardiac disease (n=20)
I
Intervention
Real-time true fast imaging with steady-state precession (FISP) cine MR imaging (one breath hold)
C
Comparator
Single-section true FISP imaging (all subjects) and segmented fast low-angle shot (FLASH) MR imaging (volunteers only)
O
Outcome
Contrast-to-noise ratios (CNRs) and left ventricular mass and function measurementssurrogate
Real-time true FISP cine MR imaging allows for accurate evaluation of left ventricular function in a single breath hold, comparable to standard multi-breath-hold techniques.
Cite This Study
Lee et al. (2002) conducted an observational in Healthy volunteers and patients with cardiac disease (n=20). Real-time true FISP cine MR imaging vs. Single-section true FISP imaging and segmented FLASH MR imaging was evaluated on Contrast-to-noise ratios (CNRs) and left ventricular mass and function measurements. Real-time true FISP cine MR imaging evaluated the entire left ventricle in one breath hold, yielding higher myocardium-to-blood CNRs than FLASH and comparable LV function to single-section FISP.