Exercise in subjects with coronary artery disease is associated with impaired systolic ejection and failure to increase mechanical efficiency, aggravating coronary reserve inadequacy.
Observational
Human subjects with coronary artery disease evaluated at rest and during exercise.
Exercise vs Rest
Cardiac performance and oxygenation
Cardiac performance and oxygenation have been studied in resting and exercising subjects with coronary artery disease. Disturbances exist in myocardial function and energetics, characterized by preservation of pressure development, but with impaired systolic ejection and failure to increase mechanical efficiency during exercise. Resultant elevation of myocardial oxygen need by impaired performance undoubtedly aggravates coronary reserve inadequacy during exercise.
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Joseph V. Messer
Cardiac Imaging
Herbert J. Levine
Wesleyan University
Richard J. Wagman
United States Department of Transportation
Circulation
Harvard University
Brigham and Women's Hospital
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Messer et al. (Sun,) conducted a observational in Coronary Artery Disease. Exercise vs. Rest was evaluated on Cardiac performance and oxygenation. Exercise in subjects with coronary artery disease is associated with impaired systolic ejection and failure to increase mechanical efficiency, aggravating coronary reserve inadequacy.
synapsesocial.com/papers/6a1f2bbee800cc4eef553d5a — DOI: https://doi.org/10.1161/01.cir.28.3.404