Early discharge within 2 days following primary percutaneous coronary intervention for STEMI was associated with a 4.3% long-term mortality rate compared to 12.3% for late discharge.
Observational (n=2,448)
Does early discharge within 2 days of admission maintain safety regarding post-discharge all-cause mortality in STEMI patients treated with PPCI compared to late discharge?
Early discharge within 2 days following primary PCI for STEMI appears safe, with low short- and long-term mortality rates.
Absolute Event Rate: 4.3% vs 12.3%
BACKGROUND: To assess safety of early discharge following primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Retrospective analysis of prospectively collected data of 2448 STEMI patients treated with PPCI surviving to hospital discharge. Post-discharge all-cause mortality was reported at 1, 7, and 30 days and long-term follow up. A total of 1542 patients (63.0%) were discharged within 2 days of admission (early discharge group) and 906 patients (37.0%) after 2 days (late discharge group). In both groups, no deaths were recorded 1 day post discharge. The early and late discharge group mortality figures for 7 days were 0 and 4 patients (0.04%) and between 7 and 30 days were 11 (0.7%) and 11 patients (1.2%), respectively. During a mean follow up of 584 days, 178 patients (7.3%) died: 67 in the early discharge group (4.3%) and 111 in the late discharge group (12.3%). CONCLUSIONS: This exploratory, observational study demonstrates that discharging low-risk STEMI patients within 2 days following PPCI is safe. For providers of health care, early discharge can help to allay the cost of providing a 24-hour PPCI service and adds to the recognized benefits arising from PPCI.
Noman et al. (Thu,) conducted a observational in ST-elevation myocardial infarction (n=2,448). Early discharge (within 2 days of admission) vs. Late discharge (after 2 days) was evaluated on All-cause mortality at long-term follow up. Early discharge within 2 days following primary percutaneous coronary intervention for STEMI was associated with a 4.3% long-term mortality rate compared to 12.3% for late discharge.
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