Early discharge after primary percutaneous coronary intervention for ST-elevation myocardial infarction
Key result
Early discharge within 2 days following primary percutaneous coronary intervention for STEMI was associated with a 4.3% long-term mortality rate compared to 12.3% for late discharge.
Why the study?
Does early discharge within 2 days of admission maintain safety regarding post-discharge all-cause mortality in STEMI patients treated with PPCI compared to late discharge?
Population
2448 STEMI patients treated with primary percutaneous coronary intervention surviving to hospital discharge
Comparison
Early discharge (within 2 days of admission) vs Late discharge (after 2 days of admission)
Design
Cohort
Follow-up
mean 584 days
Authors
Discussion
Loading...
Member takes
Implication
Supports early discharge safety in selected STEMI patients post-PPCI; leaves open need for randomized confirmation before practice change.
Study Design
Type
Observational (n=2,448)
Structured PICO
Does early discharge within 2 days of admission maintain safety regarding post-discharge all-cause mortality in STEMI patients treated with PPCI compared to late discharge?
P
Population
2,448 STEMI patients treated with primary percutaneous coronary intervention who survived to hospital discharge, followed for a mean of 584 days.
E
Exposure
Early discharge (within 2 days of admission)
C
Comparator
Late discharge (after 2 days of admission)
O
Outcome
Post-discharge all-cause mortality at 1, 7, and 30 days and long-term follow uphard clinical
Main Result
Absolute Event Rate: 4.3% vs 12.3%
Early discharge within 2 days following primary PCI for STEMI appears safe, with low short- and long-term mortality rates.
Limitations
- observational design
Cite This Study
Noman et al. (2013) conducted an observational in ST-elevation myocardial infarction (n=2,448). Early discharge (within 2 days of admission) vs. Late discharge (after 2 days) was evaluated on All-cause mortality at long-term follow up. Early discharge within 2 days following primary percutaneous coronary intervention for STEMI was associated with a 4.3% long-term mortality rate compared to 12.3% for late discharge.