Age Gap as a Biomarker of Neurodegeneration and Functional Decline in Multiple Sclerosis: Insights into Racial Differences (P11-20.003)

Key Points

• This study aims to evaluate how age gap relates to neurodegeneration and functional decline in multiple sclerosis patients, particularly focusing on racial differences.
• Evaluated the age gap in relation to neurodegeneration and functional outcomes in MS patients.
• Analyzed data for both Black and White patients separately.
• Utilized brain-predicted versus chronological ages to measure the age gap.
• Found significant relationships between age gap and neurodegeneration in the overall MS cohort.
• Identified distinct differences in microstructural and clinical outcomes between Black and White patients based on the age gap.
• Suggests potential implications for personalized treatment strategies in MS management.