In two patients with Wolff-Parkinson-White syndrome, His bundle electrograms revealed ventricular pre-excitation due to a bypass tract, and both were successfully treated with propranolol and a pacemaker.
Case Report (n=2)
Early electrophysiological study using His bundle recordings demonstrated that WPW pre-excitation bypasses the His bundle, and highlighted successful management with propranolol and demand pacing.
The catheter technic for recording the electrical activity of the specialized conducting system in the human heart showed in two patients studied that ventricular pre-excitation was apparently due to a bypass of the His bundle. Intermediate forms of WPW complexes appeared to be combination beats resulting from the activation of the ventricles through impulses traversing both the His bundle and accessory communications. Preferential iatrogenic activation of an intra-atrial (and perhaps even of an atrioventricular) tract appeared to occur in one of the patients. The patients with the WPW (pre-excitation) syndrome and long histories of paroxysmal arrhythmias were successfully treated with a combination of oral propranolol and implanted (transvenous) demand pacemaker.
Castellanos et al. (Sun,) conducted a case report in Wolff-Parkinson-White (Pre-excitation) Syndrome (n=2). Oral propranolol and implanted demand pacemaker was evaluated. In two patients with Wolff-Parkinson-White syndrome, His bundle electrograms revealed ventricular pre-excitation due to a bypass tract, and both were successfully treated with propranolol and a pacemaker.