Necropsy of two young men with Marfan's syndrome and terminal arrhythmias was performed to evaluate the pathology of their cardiac conduction system.
Case Report (n=2)
This case series describes the pathology of the cardiac conduction system in two young men with Marfan's syndrome who experienced terminal arrhythmias.
Death of patients with Marfan's syndrome is often sudden and unexpected.1It is natural under such circumstances to suspect a cardiac arrhythmia as one possible explanation. Recently it has been our opportunity to study two young men with Marfan's syndrome who developed disturbances in cardiac rhythm or conduction during their terminal illness. The following is a report of these two patients and the pathology of their cardiac conduction system at necropsy. Report of CasesCase 1. —A 20-year-old white male student twice had operations in childhood for attempted correction of severe funnel chest. Before these operations a grapefruit could allegedly be placed in the chest excavation, and one surgeon described the sternum as being "¼ inch from the backbone." The patient was 72 inches tall, had an arm span of 76½ inches, was slender (140 lb 63.5 kb), and exhibited arachnodactyly. On the skin of the anterior surface of
Thomas N. James (Tue,) conducted a case report in Marfan's syndrome (n=2). Necropsy was evaluated on Pathology of cardiac conduction system. Necropsy of two young men with Marfan's syndrome and terminal arrhythmias was performed to evaluate the pathology of their cardiac conduction system.