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August 7, 2025Angewandte Chemie International Edition

Central Dynamic Conversion of Dicyanomethyl Radicals via Intermolecular Charge Transfer for Ultrabright NIR‐II Fluorescence Imaging‐Guided Mild Photothermal Therapy

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Authors

YXYixuan XuDYDalong YinYWYating Wang

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Overview

Novel radical system demonstrates enhanced fluorescence imaging in tumors, suggesting improvements in mild photothermal therapy outcomes.

Key Points

  • The novel CNPJ radical system was engineered for high-performance fluorescence imaging and photothermal therapy.
  • CNPJ exhibits an impressive photoluminescence quantum yield of 2.57%, making it a potent tool for near-infrared applications.
  • Key mechanisms in CNPJ include intermolecular charge transfer and radical center redistribution, enhancing stability and functionality.
  • Integration with a pH-responsive polymer allows for effective imaging-guided tumor therapy, which can lead to improved treatment strategies.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/689521d79f4f1c896c427af7https://doi.org/10.1002/anie.202509609
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