Cohort study identifies seropositivity rates and genetic factors affecting seropersistence in women, highlighting implications for CT control strategies.
Key Points
Among women, 42% who were seropositive at baseline remained so six years later, indicating notable seropersistence.
Women reporting treated CT infections had significantly higher seropersistence rates, with adjusted odds ratios up to 4.79.
Demographic and host genetic factors, specifically SNPs in TLR2 and TLR9, are associated with seropositivity and seropersistence.
Understanding these factors can enhance CT-control strategies by targeting at-risk populations based on genetic predisposition.