Active screening improves tuberculosis case detection in communities, suggesting tongue swabs as a non-invasive alternative.
Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its community transmission, which depends critically on enhancing case detection. Active screening for TB in community populations is crucial in order to address the current shortfall in case detection through passive, symptom-based approaches. However, obtaining sputum specimens from these populations is challenging. In recent years, various alternative specimen types to sputum have emerged for use in active case-finding strategies for TB patients. Of these, the tongue swab is the most promising new, non-invasive specimen type for TB detection. Integrating advanced methods, such as artificial intelligence-based radiological imaging, could effectively facilitate the development of an active TB case-finding strategy in the community.
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Pang et al. (2025) studied this question.
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