July 12, 2025Virchows ArchivOpen Access

The morphological spectrum of Castleman disease and related disorders: a report from the Lymphoma Workshop of the 22nd Meeting of the European Association of Hematopathology

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Report reviews diverse features of castleman disease in 85 cases, highlighting challenges in differential diagnosis and treatment implications.

Castleman disease includes local and systemic disorders affecting lymph nodes with diverse presentations.
The report outlines 85 cases, emphasizing the need for accurate differential diagnosis and treatment strategies.
Key features of unicentric, multicentric CD, and TAFRO syndrome are discussed alongside their molecular landscapes.
Integration of clinical and molecular data is crucial for distinguishing CD from neoplastic and autoimmune mimickers.

Gašljević et al. (2025) studied this question.

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Report reviews diverse features of castleman disease in 85 cases, highlighting challenges in differential diagnosis and treatment implications.