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July 15, 2025Journal of Gastroenterology and HepatologyOpen Access

Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease

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Authors

HWHejie WangYQYaxin QuLYLin Yuan

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Overview

Systematic review finds H. pylori infection reduces GERD risk, while eradication increases it, suggesting potential implications for treatment strategies.

Key Points

  • H. pylori infection is inversely associated with GERD risk, with a pooled odds ratio of 0.58.
  • Eradication of H. pylori increases GERD risk, reflected in a pooled odds ratio of 2.01.
  • Meta-analysis combined data from 24 studies, including cohort studies and randomized controlled trials.
  • Findings may influence clinical approaches to managing GERD and H. pylori treatment strategies.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/689a02bce6551bb0af8cc7c0https://doi.org/10.1111/jgh.70009
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