Retrospective cohort study assesses mortality and morbidity in premature infants with birth defects and asphyxia, suggesting critical implications for NICU care.
Introduction: Preterm birth is a leading international health issue with morbidity and mortality risks. Premature newborns also suffer due to the presence of birth defects and asphyxia factors, which contribute to longer stays in hospitals, ventilations, and disability problems. This research investigates a composite effect of birth defects as well as birth asphyxia among premature infants on survival and recovery. Methods: The tools were a retrospective cohort study carried out in an NICU in Mecca, Saudi Arabia. We examined 120 medical records on premature infants diagnosed with birth defects or birth asphyxia to determine outcomes like mortality, morbidity, ventilation days, and unit stay Results: Infants with birth asphyxia had a lower mortality rate (13.2%) as opposed to birth defects (37.8%). The rate of improvement of infants with asphyxia (81.6%) was higher than that of infants with birth defects (58.5%). Infants who had birth defects needed more time being ventilated and being hospitalized as compared to infants with birth asphyxia. The rates of blood count and ventilation failure were higher in the birth defects group as well. Discussion: The birth defects enable the prematurity to exacerbate in levels in terms of mortality, length of stay in hospital establishment, and complications as opposed to asphyxiation during birth. Conclusion: Birth defects and birth asphyxia play an extreme role in the outcome of premature babies. Facilitation of improvements in survival and decreasing long-term complications is associated with early detection, individual attention care, and implementation of antibiotics.
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Khan et al. (2025) studied this question.
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