The Predictive Value of AGEF Score for Contrast-Induced Nephropathy in Patients with Lower Extremity Peripheral Artery Disease

Abstract Background Lower extremity peripheral artery disease (LEAD) is a disease that impairs quality of life, causes amputation and is associated with mortality. Percutaneous interventions are performed for therapeutic purposes in patients with LEAD. Contrast-induced nephropathy (CIN) may emerge due to the contrast media used during these interventions. This study aimed to investigate the predictive value of six scoring systems including AGEF, ACEF, Zhi-Feng Yao, CR4EATME3AD3, Mehran, and Tziakas for CIN. Methods This retrospective study included 690 patients with LEAD. The study population was divided into two groups according to presence of CIN. Results In our study, the AGEF, ACEF, Tziakas, Zhi-Feng Yao, CR4EATME3AD3, and Mehran scoring systems demonstrated robust predictive capabilities for the development of CIN following percutaneous intervention in patients with LEAD. Moreover, the AGEF, Zhi-Feng Yao, CR4EATME3AD3, and Mehran scores were identified as independent predictors of CIN development in patients with LEAD revascularized via endovascular interventions. Conclusion The findings of this study revealed that various scoring systems performed well in predicting CIN in LEAD patients. In addition, among these scoring systems, AGEF has been shown to be the best in terms of predictive power.