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August 4, 2025

Table 1 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes

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Authors

DMDimitrios MathiosWashington University in St. LouisNNNoushin NiknafsJohns Hopkins UniversityAAAkshaya V. AnnapragadaJohns Hopkins University

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Overview

Research demonstrates detection of brain cancer using genome-wide cell-free DNA fragmentomes in patient cohorts, suggesting a new diagnostic approach.

Key Points

  • MAIN FINDING: The study identifies genome-wide cell-free DNA fragmentomes as a method for detecting brain cancer.
  • KEY EVIDENCE: Analysis reveals significant differences in fragmentomes between brain cancer patients and healthy controls.
  • APPROACH: The research includes discovery and validation cohorts to support findings and enhance reliability.
  • SIGNIFICANCE: This method could improve early diagnosis and treatment strategies for brain cancer patients.

Cite This Study

Mathios et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0938https://doi.org/10.1158/2159-8290.29819617
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