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August 5, 2025Frontiers in PharmacologyOpen Access

Melatonin: a natural guardian in cancer treatment

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Authors

YCYu-Rou CaoHZHang ZhangXCXiang-Rong Chen

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Overview

Melatonin improves anticancer effects in tumors, suggesting potential in personalized therapy alongside traditional drugs.

Key Points

  • Melatonin exhibits significant anticancer effects through various mechanisms, including tumor apoptosis.
  • The hormone enhances the efficacy of other drugs, like cisplatin and paclitaxel, in cancer treatment.
  • Targeted delivery methods help address melatonin's low bioavailability and rapid metabolism during treatment.
  • Individualized therapy can optimize melatonin's application, making it a strong candidate for future treatments.

Cite This Study

Cao et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d126bhttps://doi.org/10.3389/fphar.2025.1617508
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Also Consider

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  1. 1Melatonin as an anti-cancer agent: mechanistic targeting of the PI3K/Akt signaling pathway2026
  2. 2Melatonin and Virus induced Oncogenic Factors2025
  3. 3Antitumor Effects of Melatonin in Luminal and Triple-Negative Breast Cancer Cells: Metabolic Reprogramming, Redox Regulation, and Cellular Dynamics2026
  4. 4Repurposing melatonin for its potential roles in gastrointestinal cancers: highlighting the molecular mechanisms2026
  5. 5Melatonin and Selected Phytochemicals: A Promising Combination to Target Altered Metabolism in Cancer2026 · 1 citations