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August 5, 2025

A Qualitative Systematic Review of Cognitive Function, Metabolic Alterations, Disordered Eating, and Mood Dysregulation in the Context of the Mind–Body Connection

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Authors

VPVarvara PapasideriSCStylianos Sergios Chatziioannou

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Overview

Qualitative review identifies links between metabolic alterations, mood dysregulation, and disordered eating, suggesting integrated care models.

Key Points

  • Cognitive function and metabolic alterations interact in complex ways, especially in obesity.
  • The review found that depression mediates the effects of metabolic dysfunction on cognitive performance.
  • A total of 123 studies were reviewed, highlighting diverse populations and significant themes.
  • Integrated health approaches are suggested to address cognitive, emotional, and metabolic health interconnections.

Cite This Study

Papasideri et al. (2025) studied this question.

synapsesocial.com/papers/689a0f99e6551bb0af8d1442https://doi.org/10.21203/rs.3.rs-7278470/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neuropsychological and metabolic interconnectivity in obesity, anorexia and bulimia nervosa – an integrative literature review2026
  2. 2Metabolic dysfunction in youth with major mood disorders: Implications for prevention and early intervention.2024 · 1 citations
  3. 3OBESITY AS A FACTOR AFFECTING COGNITIVE FUNCTIONS: NEUROBIOLOGICAL AND METABOLIC MECHANISMS – A REVIEW OF CURRENT EVIDENCE2026
  4. 4The Interplay Between Insulin Resistance, Affective Dysregulation, and Binge Eating in Obesity: Toward an Integrated Biopsychosocial Treatment Model2026
  5. 5Disordered Minds, Disordered Meals: When Emotions Masquerade as Hunger in Eating Disorders—A Systematic Review2026