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Implementation of CDS for drug-gene interactions improved prescribing practices in 42,000 patients, indicating that pharmacogenomics can enhance clinical outcomes.
Pharmacogenomics (PGx) has the potential to improve prescribing practices. In 2012, our institution developed a multidisciplinary program to implement PGx-CDS to support the clinical practice. CDS has been implemented for 45 drug-gene interactions, in 42,000 patients with PGx tests results, and in 2023, approximately 9281 CDS interventions have triggered at the time of prescribing. The program has been successful.
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Caraballo et al. (2025) studied this question.
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