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Case report highlights stable bilateral optic nerve calcification in a female with Graves disease, suggesting no functional compromise.
A 61-year-old female patient with a previous diagnosis of Graves disease and mild orbitopathy presented with bilateral optic nerve calcifications and multiple areas of intracranial calcification. Neuro-ophthalmological evaluation did not detect any functional or anatomical compromise of the optic nerves. Her renal function and serum levels of calcium, phosphorus, and parathyroid hormone were normal. Two CT scans of the orbits, performed 7 years apart, showed stable intracranial and bilateral optic nerve calcifications.
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Passarini et al. (2025) studied this question.
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