Case report reveals ovarian carcinosarcoma in a renal transplant recipient, highlighting immunosuppression risks.
Background: Post-transplant malignancies are a recognized complication of long-term immunosuppression in renal transplant recipients, with incidences significantly higher than in the general population [1,2]. Ovarian carcinosarcoma remains a particularly rare and aggressive post-transplant tumour [3]. Case Presentation: A 54-year-old female renal transplant recipient presented with progressive abdominal distension and weight loss 3 years post-transplant. Imaging revealed massive ascites and a large complex ovarian mass. Histopathology confirmed carcinosarcoma of the ovary. Despite initiation of chemotherapy, the patient died three weeks later. Conclusion: This case highlights the importance of heightened surveillance for rare malignancies in immunosuppressed transplant recipients. Ovarian carcinosarcoma is a rare but fatal diagnosis, necessitating prompt intervention and potential immunosuppression adjustment.
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Loskurima et al. (2025) studied this question.
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