Case report demonstrates stable disease following chemoradiotherapy and CVD chemotherapy in recurrent carotid body tumors, suggesting a potential treatment option.
Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences. This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs.
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Liu et al. (2025) studied this question.
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