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August 12, 2025Pain MedicineOpen Access

Baseline characteristics of participants in the Biomarkers for Evaluating Spine Treatments clinical trial: a sequential multiple assignment randomized trial for chronic low back pain†

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Authors

BRBryce RowlandUniversity of North Carolina at Chapel HillKBKelly S. BarthMedical University of South CarolinaKBKevin M. BellUniversity of Pittsburgh

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Implication

Randomized trial investigates pain treatment effectiveness in chronic low back pain patients, suggesting biomarker use for personalized therapy.

Key Points

  • The trial enrolled 805 participants for treatment, showcasing a diverse sample of chronic low back pain patients across multiple sites.
  • Chronic low back pain affects many in the US, necessitating effective treatment options based on individual characteristics.
  • Phenotyping was conducted on 805 randomized participants to improve treatment response predictions amidst various demographic backgrounds.
  • The study highlights the feasibility of collecting extensive phenotypic data in clinical trials, enhancing treatment optimization for chronic conditions.

Cite This Study

Rowland et al. (2025) studied this question.

synapsesocial.com/papers/68a3633d0a429f7973329e99https://doi.org/10.1093/pm/pnaf073
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Also Consider

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