Monte Carlo simulation reveals causal link between depolarization metrics and microscopic interactions in samples with nanospheres, indicating potential for biomedical applications.
Polarimetric measurements hold significant potential in biomedical imaging, particularly for revealing structural details and enabling early detection of certain pathologies via depolarizing characteristics. This study presents a polarization-based Monte Carlo simulation to model Mueller matrices of samples doped with spherical nanoparticles under varying conditions. This approach enables the establishment of a causal relationship between microscopic light-matter interactions and macroscopic depolarization metrics. Experimental validation on diverse samples measured with a complete polarimeter demonstrates adaptability for inferencing nanoscale materials attribution. The integration of causal inference advances the understanding of depolarization mechanisms, paving the way for precise sample analysis and biomedical applications.
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Mao et al. (2025) studied this question.
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