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August 16, 2025Open Access

Silyl Chloroalkenyl and Alkynyl Sulfur Pentafluorides as versatile reagents to access novel fundamental SF5 building blocks

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Authors

PBPhilipp BohnLXLujie XuSPSharon Pinus

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Overview

This research demonstrates efficient synthesis of diverse SF5 building blocks using a stable platform reagent, suggesting new pathways for organic synthesis.

Key Points

  • The study shows that silylated SF5 alkynes enable the production of various SF5-containing building blocks.
  • High yields of up to 99% were achieved for (E)-configured vinyl sulfides through nucleophilic substitution.
  • Analysis used a versatile platform reagent, highlighting a novel in-situ elimination strategy for synthesis.
  • Development contributes to overcoming accessibility restrictions for sulfur pentafluoride derivatives, increasing practical applications.

Cite This Study

Bohn et al. (2025) studied this question.

synapsesocial.com/papers/68a366b20a429f797332ce29https://doi.org/10.26434/chemrxiv-2025-jmfh6
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