This mechanochemical approach achieves regioselective C5-sulfenylation of imidazo[2,1-b]thiazoles, highlighting the potential for sustainable green synthesis.
The Cover Feature highlights a sustainable, metal-free mechanochemical strategy for the regioselective C5-sulfenylation of imidazo[2,1-b]thiazoles by using PIFA and aryl methyl sulfides. This solvent-free approach enables rapid and eco-friendly heterocycle functionalization under ball-milling conditions, thus offering a valuable tool for green synthesis. More information can be found in the Research Article by J.-F. Soulé, A. Hamze and co-workers (DOI: 10.1002/cssc.202500320).
No takes yet. Share an insight, caveat, or question.
Liu et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: