Ligation achieves high selectivity and quantitative coupling in low concentrations using S N Ar and CuAAC chemistry.
Ligation of two short REMO strands on a longer sequence-complementary template gives quantitative coupling reactions at very low concentrations and with very high selectivity using either S N Ar or CuAAC chemistry.
No takes yet. Share an insight, caveat, or question.
Beale et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: