Comparative study evaluates acoustical properties of antibiotic drugs in aqueous solutions, suggesting unique molecular interactions.
Density, viscosity and ultrasonic velocity measured experimentally for the aqueous solutions of ceftriaxone sodium, cefotaxime sodium and ampicillin sodium with different concentrations and temperature and 2MHz frequency. Acoustical and thermodynamic parameters such as Wada’s constant, Rao’s constant, relative association, specific acoustic relaxation time, free volume, adiabatic compressibility, intermolecular free length, specific acoustic impedance and apparent molar volume determine from experimental data. The results have been interpreted to comparative study of molecular interactions in the aqueous solution of Ceftriaxone sodium, Ampicillin sodium and Cefotaxime sodium.
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Rajesh S. Hajare (2025) studied this question.
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