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August 17, 2025Messenger of Anesthesiology and ResuscitationOpen Access

The role of extracorporeal blood purification in correcting intoxication markers in septic shock: a prospective interventional controlled study

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Authors

СМС. В. МасолитинДПД. Н. ПроценкоМММ. А. Магомедов

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Overview

Prospective interventional study observes combined extracorporeal blood purification reduces inflammation markers in septic shock patients with acute kidney injury, highlighting clinical benefits.

Key Points

  • Combined extracorporeal blood purification significantly reduced C-reactive protein levels from 223.5 to 140.9 mg/L during early treatment.
  • Interleukin-6 levels decreased by 71.1% in patients undergoing combined therapy, outperforming other treatment groups.
  • Patients who received continuous veno-venous hemodiafiltration showed minimal reduction in inflammatory markers compared to combined EBP.
  • Improvement in cystatin-C levels indicates better kidney function with combined EBP compared to isolated renal replacement.

Cite This Study

Масолитин et al. (2025) studied this question.

synapsesocial.com/papers/68a36a480a429f797332eb93https://doi.org/10.24884/2078-5658-2025-22-4-17-30
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