Pregnancy-specific biological substance adjuncts rejuvenating chronic non-healing ulcer

During the LUCS of the operation theatre (OT), the newly collected human amniotic fluid membrane and amniotic fluid of thoroughly examined mothers are used to treat chronic non-healing ulcers, including burns in various body parts. Several scientists have dried chemically and heat-treated human amniotic membranes (dHAM), which are used clinically to close and protect wounds from infection. The newly collected amniotic membranes were also used to treat burns and other non-healing ulcers. The main advantage of this method is that the persistence of cellular components, growth factors, and cytokines is newly collected and remains intact, as they are not artificially processed or dried and are not combined as a biological framework or as a suitable biological bandage for healing wounds and ulcers. Amniotic fluids also contain cellular substances having wound-healing properties. Amniotic membrane and amniotic fluid also have immunomodulatory effects and inhibit inflammatory responses. Pregnancy-specific substances have the potential for future clinical use in regenerative medicine and translation science.